From Milan (380 km):
following motorway A1 direction Rome, exit at Firenze Certosa, follow Florence-Siena highway till Siena Sud, take SR2 (Cassia) direction Rome. Bypass Monteroni d'Arbia, exit at Monteroni Sud, follow signs to Rome, turn first right to Murlo, Vescovado,7 km up the hill.
From Rome (240 km):
1) take SR2 (Cassia) to Siena direction, leave it at Buonconvento, turn left to Murlo, where you arrive after 9 km.
2) take motorway A1 in Florence direction, exit at Chiusi, follow SS146 Siena direction, bypass Chianciano Terme, take SR2 (Cassia) Siena direction till Buonconvento; turn left to Murlo.
From Grosseto (55 km):
take and follow Grosseto - Siena highway SS223 for 50 km, turn right at Fontazzi/Casciano/SR2 following signs to Murlo.
The nearest railway stations are in Monteroni d'Arbia and Buonconvento www.trenitalia.com.
There is a direct bus service between Siena and Monteroni to Murlo: www.trainspa.it.